The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP1) protein, CRLR functions as a CGRP receptor. The RAMP1 protein is involved in the terminal glycosylation, maturation, and presentation of the CGRP receptor to the cell surface.
|Product Type||GPCR Expressing Cell|
|Catalog||Product Name||Gene Name||Species||Morphology||Price|
|ACC-RG0584||Human CALCR+RAMP1/Gs Stable Cell Line-1321N1||RAMP1||Human||Glial||INQUIRY|
|ACC-RG1135||Human CALCRL+RAMP1 Validated Stable Cell Line-CHO||RAMP1||Human||Epithelial-like||INQUIRY|
|ACC-RG1256||Human CALCRL+RAMP1/Apoaequorin Stable Cell Line-CHO||RAMP1||Human||Epithelial-like||INQUIRY|
|ACC-RG1428||Human CALCRL+RAMP1/beta-Arrestin Stable Cell Line-CHO||RAMP1||Human||Epithelial-like||INQUIRY|