CCR8 (C-C chemokine receptor type 8) is a receptor for the chemokines CCL1 (I-309). The receptor regulates monocyte chemotaxis and thymic cell line apoptosis, and is an additional alternative coreceptor with CD4 for HIV-1 infection. CCR8 plays a role on cell types of relevance to respiratory diseases such as asthma, chronic obstructive pulmonary disease (COPD) and chronic bronchitis. The interference of CCR8 from its ligand represents a new approach in allergy therapy.
Product Information | |
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Catalog #: | ACC-RG0208 |
Gene Name | CCR8 |
Abbr | HEK293T-HuCCR8-FLAG |
Alias | CCR8,CMKBR8,CMKBRL2,CDw198,CKR L1,CY6,GPR CY6,TER1,CCR-8,CKRL1,CMKBR8,GPRCY6,CMKBRL2,CC-CKR-8,MGC129966,MGC129973 |
Growth Properties | Adherent |
Host Cell | HEK293T |
Morphology | Epithelial |
Shipping | Dry ice |
Product Type | GPCR Expressing Cell |
Species | Human |
Product Format | frozen |
searchKeyword | CCR8,CMKBR8,CMKBRL2,CDw198,CKR L1,CY6,GPR CY6,TER1,CCR-8,CKRL1,CMKBR8,GPRCY6,CMKBRL2,CC-CKR-8,MGC129966,MGC129973 |
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