CXCR7 (or RDC1) is a recently deorphanized G-protein coupled receptor which binds with high affinity the inflammatory and homing chemokines CXCL11/ITAC and CXCL12/SDF-1. CXCR7 is expressed in bladder, spleen, heart, skeletal muscle, peripheral nervous system and placenta. CXCR7 does not mediate typical chemokine receptor responses such as leukocyte trafficking. Recent findings in zebrafish indicate that a critical activity of the receptor is scavenging of CXCL12 thereby generating guidance cues for CXCR4-dependent migration.
Product Information | |
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Catalog #: | ACC-RG0228 |
Gene Name | CXCR7 |
Abbr | HEK293T-HuCXCR7-FLAG |
Alias | CXCR7,CMKOR1,GPR159,RDC1,RDC-1,CMKOR1,CXC-R7,CXCR-7 |
Growth Properties | Adherent |
Host Cell | HEK293T |
Morphology | Epithelial |
Shipping | Dry ice |
Product Type | GPCR Expressing Cell |
Species | Human |
Product Format | frozen |
searchKeyword | CXCR7,CMKOR1,GPR159,RDC1,RDC-1,CMKOR1,CXC-R7,CXCR-7 |
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