GPR41 or free fatty acid receptor 3 (FFAR3) shares 98% amino acid identity with GPR42 and closely related to GPR43. While GPR43 is expressed in immune cells, GPR41 appears to be expressed in blood vessel endothelial cells, particularly in adipose tissue, with significant expression also in immune cells and endothelial cells of other tissues. Although propionate and short chain fatty acids were identified recently as the cognate physiological ligands for GPR41, the functional roles of the receptor is still not clear and awaits the development of specific high affinity agonist and antagonists and the evaluation of knock-out animals.
Product Information | |
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Catalog #: | ACC-RG0254 |
Gene Name | FFAR3 |
Abbr | HEK293T-HuFFAR3-FLAG |
Alias | FFAR3,GPR41,FFA3R |
Growth Properties | Adherent |
Host Cell | HEK293T |
Morphology | Epithelial |
Shipping | Dry ice |
Product Type | GPCR Expressing Cell |
Species | Human |
Product Format | frozen |
searchKeyword | FFAR3,GPR41,FFA3R |
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