Gastric inhibitory polypeptide receptor (GIP) has been identified in the glucose-mediated secretion of insulin. GIP is in the secretin/VIP receptor family which includes secretin, VIP, glucagon, GLP-1, growth hormone releasing hormone (GHRH), and PACAP. GIP is secreted after meal ingestion has been shown to stimulate bone formation resulting in lower occurrences of osteoporosis. Type 2 diabetes is a result of decreased glucose-stimulated insulin secretion which makes insulin secretion potentiators a popular target for diabetes treatments, it is thought that a defect in GIP expression and/or signaling may lead to beta-cell dysfunction and type 2 diabetes.
Product Information | |
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Catalog #: | ACC-RG0664 |
Gene Name | GIPR |
Abbr | Chem-9-HuGIPR/Galpha15 |
Alias | GIPR,GIP-R,PGQTL2,MGC126722 |
Growth Properties | Adherent |
Host Cell | Chem-9 |
Shipping | Dry ice |
Product Type | GPCR Expressing Cell |
Species | Human |
Product Format | frozen |
searchKeyword | GIPR,GIP-R,PGQTL2,MGC126722 |
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