GPR68, also known as OGR1 (ovarian cancer G-protein-coupled receptor 1), was initially thought to be a receptor for sphingosylphosphorylcholine, although these results are controversial. Subsequent studies indicated that GPR68/OGR1 functions as a Gq-coupled sensor for extracellular pH, with maximal signaling occurring at pH of 7 or below. Expression of GPR68/OGR1 is upregulated during RANKL-induced osteoclast differentiation, and knockdown of GPR68/OGR1 expression inhibits this differentiation process.
Product Information | |
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Catalog #: | ACC-RG0760 |
Gene Name | GPR68 |
Abbr | Chem-1-HuGPR68/Galpha15 |
Alias | GPR12A,OGR1 |
Growth Properties | Adherent |
Host Cell | Chem-1 |
Shipping | Dry ice |
Product Type | GPCR Expressing Cell |
Species | Human |
Product Format | frozen |
searchKeyword | GPR12A,OGR1 |
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Catalog | Product Name | Gene Name | Species | Morphology | Price |
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ACC-RG1663 | Human GPR68 Stable Cell Line-CHO-K1/Gα15 | GPR68 | Human | INQUIRY |
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