Leukotriene and related receptors are activated by the endogenous ligands leukotriene (LT) B4, LTC4, LTD4, LTE4 and 12-HETE. Leukotrienes are lipid mediators synthesized from arachidonic acid by lipoxygenase enzymes. They act on peroxisome-proliferating receptors (PPARs) as well as the G-protein-coupled leukotriene receptors, and are important in inflammatory signaling pathways. Leukotriene and related receptors are high affinity stereoselective receptors that have a wide biological distribution. BLT1 and BLT2 receptors are synthesized by polymorphonuclear leukocytes and are found at their highest concentrations on myeloid cells, mast cells and macrophages.
Product Information | |
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Catalog #: | ACC-RG0679 |
Gene Name | LTB4R |
Abbr | Chem-1-HuLTB4R/Galpha15 |
Alias | LTB4R,CMKRL1,GPR16,P2RY7,BLTR,LTB4R1,P2Y7,LTB4-R1,LTB4-R 1,BLT1,GPR16,LTBR1,P2RY7,CMKRL1 |
Growth Properties | Adherent |
Host Cell | Chem-1 |
Shipping | Dry ice |
Product Type | GPCR Expressing Cell |
Species | Human |
Product Format | frozen |
searchKeyword | LTB4R,CMKRL1,GPR16,P2RY7,BLTR,LTB4R1,P2Y7,LTB4-R1,LTB4-R 1,BLT1,GPR16,LTBR1,P2RY7,CMKRL1 |
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