Vasoactive intestinal peptide (VIP), a 28 amino acid peptide originally isolated by its vasodilation activity, binds to two class B GPCRs, VPAC1 and VPAC2, to exert its functions in the CNS, vasculature, immune system and adrenal medulla. In the immune system, VPAC2 is expressed on stimulated CD4 T cells, and binding of T cell-derived VIP to VPAC2 induces a shift toward the Th2 pathway. In addition, VPAC2 is an essential regulator of the circadian pacemaker of the hypothalamic suprachiasmatic nuclei.
Product Information | |
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Catalog #: | ACC-RG0773 |
Gene Name | VIPR2 |
Abbr | Chem-1-HuVIPR2/Galpha15 |
Alias | VIPR2,VPAC2,VPAC2R,VIP-R-2,VPCAP2R,PACAP-R3,DUP7q36.3,PACAP-R-3,C16DUPq36.3,FLJ16511 |
Growth Properties | Adherent |
Host Cell | Chem-1 |
Shipping | Dry ice |
Product Type | GPCR Expressing Cell |
Species | Human |
Product Format | frozen |
searchKeyword | VIPR2,VPAC2,VPAC2R,VIP-R-2,VPCAP2R,PACAP-R3,DUP7q36.3,PACAP-R-3,C16DUPq36.3,FLJ16511 |
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ACC-RG1713 | Human VIPR2 Stable Cell Line-CHO-K1/Gα15 | VIPR2 | Human | INQUIRY | |
ACC-RG1345 | Human VIPR2/Apoaequorin Stable Cell Line-CHO | VIPR2 | Human | Epithelial-like | INQUIRY |
ACC-RG0477 | Human VIPR2/Gs Stable Cell Line-CHO | VIPR2 | Human | Epithelial-like | INQUIRY |
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