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Fluorescence Assay

Fluorescence assays employ membrane potential dye or FRET-based voltage senor to measure fluorescence changes caused by dye relocation in response to membrane potential depolarization or hyperpolarization following ion channel activation or inhibition.

In Creative Bioarray, our high throughput ion channel screening team incorporate to design, optimize and run ion channel High Throughput Screening programs with a clear focus on ensuring meaningful data and successful outcomes within client-driven timelines.

  • Fluorescence-based FLIPR assays

  • Automated 384-well electrophysiology

With a dedicated ion cell biology team on hand, Creative Bioarray can rapidly screen compounds against even the most challenging ion channel targets.


1-1-2 Fluorescence Assay.jpg

Fig. 1 Pipeline of high-throughput screening targeting ion channels


Reference

  1. Haibo, Y., et al. High throughput screening technologies for ion channels, Acta Pharmacologica Sinica. 2016; 37: 34-43


For research use only.

Related Section

  • Ion Flux Assay
  • Patch-clamp Assay

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