For more than 80 ion channels, including voltage-gated channels (e.g., Na⁺ channels, K⁺ channels and Ca²⁺ channels) and ligand-gated channels (e.g. TRP, NACHR, P2X channels), Creative Bioarray offers all cell based functional assays. We have built an extensive ion channel screening panel which would meet your demands no matter for academic research or commercial analysis.

Table. 1 Current Ion Channel Drugs

As an experienced expert skilled in electrophysiological experiments, Creative Bioarray offers you with primary screening and functional profiling assays to help you discover potential compounds targeting ion channels. We provide you deep understanding of the relationship and interaction between your compounds and ion channel target. Based on the prompt communication and on-time reporting, Creative Bioarray is dedicating working closely with your team to accelerating your project with the most competitive price.

Advantages

• State-of-the-art of the gold standard manual patch clamp technology

• Variety of automated platform assays to meet different demands

• Reliable and short turn-around time

Ion Channel Screening Library

Creative Bioarray has developed comprehensive validated screening & profiling assays and a library of stable channel-expressing cell lines for high throughput screening, lead optimization studies and selectivity profiling. All our tests have been validated by experienced electrophysiologists under stringently optimized SOPs to guarantee highest quality and consistency data are provided.

Fig 1. Ion channel diversity. The chart shows the major ion channel subfamilies with the size of each sector being proportional to the number of channels within that subfamily

We Provide you with a comprehensive screening library listed by not limited as followings:

• Sodium Channels

• Calcium Channels

• Potassium Channels

• Chloride Channels

• TRP Channels

• ATP gated P2X Channels

• ASICs

• nicotinic Acetylcholine receptors

• ionotropic Glutamate-gated Receptors

• GABAa Receptors

• Glycine Receptors

• 5-HT Receptors

• Cystic Fibrosis Transmembrane Conductance Regulators (CFTR)

• Other Ion Channels

Quotation and Ordering

If you have any special needs in our Ionic Screening Panel Service, please contact us at Email or Telephone for this special service. Let us know what you need and we will accommodate you. We look forward to working with you in the future.

References

1. Clare J J. Targeting ion channels for drug discovery. Discovery medicine. 2010; 9: 253-260.

2. Wu, Z., et al. Ion channels gated by acetylcholine and serotonin: structures, biology, and drug discovery. Acta Pharmacologica Sinica. 2015; 36: 895–907.

Related Section

• Ionic Screening Service
• Stable Cell Lines