Channelomic studies screen potential drugs for their effectiveness at channelopathies, by examining the binding affinities of candidate drug compounds, by a variety of techniques, including patch clamp electrophysiology, PCR, and immunohistochemistry.

Acroscell is your ideal and reliable innovation partner in research endeavors. We have a comprehensive cell bank with a variety of specialized and unique stable cell lines expression ion channels that can be applied to a variety of in vitro research and in vivo pharmacology study instantly.

Patch-Clamp Recording Protocol

The major limitation of in vivo patch-clamp recording is its technical difficulty, which requires experienced personnel and a large amount of patience. The workflow of patch-clamp recording involves pressing a glass micropipette against a cell in order to isolate a small "patch" of membrane that contains one or more ion channel...

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The Patch-Clamp Technique

Cellular physiological properties are closely related to the biological, chemical and physical properties of cells. The patch clamp technique is a laboratory technique in electrophysiology, which is used to study ionic currents in individual isolated living cells, tissue sections, or patches of cell membrane, investigating cellular physiological function...

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Related Section

• Patch-Clamp Recording Protocol
• The Patch-Clamp Technique