Our specialized electrophysiology services in intact systems provide direct evidence of drug efficacy and mechanisms of action. We provide recordings performed in a range of states, including neuropathic, inflammatory and neurodegenerative models, etc. Responses can be compared to in-house reference data generated using ‘gold standard’ compounds (e.g. gabapentin and morphine). Compound effects on mechanically, electrically and/or chemically evoked responses can all be studied utilizing a range of electrophysiological techniques.
Specialized electrophysiology at Acroscell includes:
Single/multi-unit and field potential recordings
Recordings from all characterized brain regions and nuclei
Recordings from the spinal cord (e.g. dorsal horn neurons) and dorsal roots
Peripheral nerve (whole nerve/single fibres)
Peripheral ganglia (single/multi-unit)
Whole organs/muscle groups as ECG/EMG/EEG
If you have any special requirements / related questions, please do not hesitate to contact us. Our experts will do their best to assist you.