Our specialized electrophysiology services in intact systems provide direct evidence of drug efficacy and mechanisms of action. We provide recordings performed in a range of states, including neuropathic, inflammatory and neurodegenerative models, etc. Responses can be compared to in-house reference data generated using ‘gold standard’ compounds (e.g. gabapentin and morphine). Compound effects on mechanically, electrically and/or chemically evoked responses can all be studied utilizing a range of electrophysiological techniques.

Specialized electrophysiology at Creative Bioarray includes:

CNS:

• Single/multi-unit and field potential recordings

• Recordings from all characterized brain regions and nuclei

• Recordings from the spinal cord (e.g. dorsal horn neurons) and dorsal roots

PNS:

• Peripheral nerve (whole nerve/single fibres)

• Peripheral ganglia (single/multi-unit)

• Whole organs/muscle groups as ECG/EMG/EEG

If you have any special requirements / related questions, please do not hesitate to contact us. Our experts will do their best to assist you.

Related Section

• Action Potential Properties Assay
• NMDA/AMPA Ratio Test
• Calcium Signaling Test