Norepinephrine is implicated in a wide range of physiological processes through activation of nine different G-protein-coupled receptors (alpha1a, alpha1b, alpha1d, alpha2a, alpha2b, alpha2c, beta1, beta2, beta3). The alpha1B-adrenoceptor expresses in brain, heart, kidney, and artery of various mammalian species and mediate diverse effects on cardiac functions, muscle contractions and cell growth. The knockout mouse models lacking the alpha1b-adrenergic receptor has highlighted the potential implication of this receptor subtype in variety of functions including the regulation of blood pressure, glucose homeostasis, reproduction, and the rewarding response to drugs of abuse. In vitro and in vivo studies also indicate that the alpha1b gene can function as an oncogene inducing neoplastic transformation.
Product Information | |
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Catalog #: | ACC-RG0169 |
Gene Name | ADRA1B |
Abbr | CHO-HuADRA1B-FLAG |
Alias | ADRA1B,ADRA1,ALPHA1BAR |
Growth Properties | Adherent |
Host Cell | CHO-K1 |
Morphology | Epithelial-like |
Shipping | Dry ice |
Product Type | GPCR Expressing Cell |
Species | Human |
Product Format | frozen |
searchKeyword | ADRA1B,ADRA1,ALPHA1BAR |
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