Human ADRA2C Stable Cell Line-CHO-K1/Gα15

Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. The mouse studies revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons. The alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes the alpha2C subtype, which contains no introns in either its coding or untranslated sequences.

Product Information
Catalog #:	ACC-RG1648
Gene Name	ADRA2C
Host Cell	CHO-K1/Gα15
Shipping	Dry Ice
Product Type	GPCR Expressing Cell
Species	Human
Product Format	frozen
searchKeyword	ADRA2C