Apelin peptides have been discovered to be a family of peptides of different sizes that is derived from the N-terminus of a 77 amino acid precursor peptide (preproapelin). Apelin receptor (APJ) is a G protein-coupled receptor that is activated by several apelin fragments, which results in inhibition of cAMP production. APJ and apelin peptides have been found to be involved in the regulation of cardiovascular function and fluid homeostasis. Broad roles of apelin system has been established in lowering blood pressure, as a potent cardiac inotrope, in modulating pituitary hormone release and food and water intake, in stress activation, and as a novel adipokine that is excreted from fat cells and regulates insulin.
Product Information | |
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Catalog #: | ACC-RG0616 |
Gene Name | APLNR |
Abbr | Chem-5-HuAPLNR/Galpha15 |
Alias | APLNR,APJ,APJR,FLJ90771,HG11,AGTRL1,FLJ96609,MGC45246 |
Growth Properties | Adherent |
Host Cell | Chem-5 |
Shipping | Dry ice |
Product Type | GPCR Expressing Cell |
Species | Human |
Product Format | frozen |
searchKeyword | APLNR,APJ,APJR,FLJ90771,HG11,AGTRL1,FLJ96609,MGC45246 |
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