CCR3 (C-C chemokine receptor type 3 or eosinophil eotaxin receptor) is a receptor for a C-C type chemokine and binds to eotaxin, eotaxin-3, MCP-3, MCP-4, RANTES and MIP-1 delta. The receptor subsequently transduces a signal by increasing the intracellular calcium level. Similar to CCR2, it is another alternative coreceptor with CD4 for HIV-1 infection. CCR3 is expressed on eosinophils, basophils, mast cell subpopulations, activated Th2 cells, macrophages and airway epithelial cells. Hence, CCR3 is closely associated with asthma and allergy and blockade of this receptor may have pronounced beneficial effects in these diseases.

Product Information
Catalog #:	ACC-RG0201
Gene Name	CCR3
Abbr	HEK293T-HuCCR3-FLAG
Alias	CCR3,CMKBR3,CC CKR 3,CD193,CKR3,CCR-3,CC-CKR-3,MGC102841
Growth Properties	Adherent
Host Cell	HEK293T
Morphology	Epithelial
Shipping	Dry ice
Product Type	GPCR Expressing Cell
Species	Human
Product Format	frozen
searchKeyword	CCR3,CMKBR3,CC CKR 3,CD193,CKR3,CCR-3,CC-CKR-3,MGC102841

Related Products

Catalog	Product Name	Gene Name	Species	Morphology	Price
ACC-RG1140	Human CCR3 Validated Stable Cell Line-K562	CCR3	Human	Lymphoblast	INQUIRY
ACC-RG0200	Human CCR3-FLAG Stable Cell Line-HEK293T Galphaqi5	CCR3	Human	Epithelial	INQUIRY
ACC-RG1260	Human CCR3/Apoaequorin Stable Cell Line-CHO	CCR3	Human	Epithelial-like	INQUIRY