CCR7 is a GPCR that binds to CC chemokine ligands MIP-3beta (ELC/CCL19) and 6Ckine (CCL21). These ligands are expressed in the secondary lymphoid organs, and binding to CCR7 expressed in naive T cells, B cells and dendritic cells directs migration of these cells to sites of antigen presentation. Inhibition of CCR7/ligand interactions inhibits contact sensitivity, delayed type hypersensitivity, and graft vs host disease in experimental models. In addition, CCR7 expression by breast cancer, melanoma and other malignant cells are associated with lymph node metastasis.

Product Information
Catalog #:	ACC-RG1262
Gene Name	CCR7
Abbr	CHO-HuCCR7/Apoaequorin
Alias	CCR7,CMKBR7,EBI1,BLR2,CD197,CDw197,CCR-7,CC-CKR-7,C-C CKR-7,EBI1,CMKBR7
Growth Properties	Adherent
Host Cell	CHO-K1
Morphology	Epithelial-like
Shipping	Dry ice
Product Type	GPCR Expressing Cell
Species	Human
Product Format	frozen
searchKeyword	CCR7,CMKBR7,EBI1,BLR2,CD197,CDw197,CCR-7,CC-CKR-7,C-C CKR-7,EBI1,CMKBR7

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