- Home
-
Screening
- Ionic Screening Service
-
Ionic Screening Panel
- Sodium Channels
- Potassium Channels
- Chloride Channels
- Calcium Channels
- TRP Channels
- ATP gated P2X Channels
- ASICs
- Nicotinic Acetylcholine Receptors
- Ionotropic Glutamate-gated Receptors
- GABAa Receptors
- Glycine Receptors
- 5-HT Receptors3
- Cystic Fibrosis Transmembrane Conductance Regulators (CFTR)
- Other Ion Channels
- Stable Cell Lines
- Cardiology
- Neurology
- Ophthalmology
-
Platform
-
Experiment Systems
- Xenopus Oocyte Screening Model
- Acute Isolated Cardiomyocytes
- Acute Dissociated Neurons
- Primary Cultured Neurons
- Cultured Neuronal Cell Lines
- iPSC-derived Cardiomyocytes/Neurons
- Acute/Cultured Organotypic Brain Slices
- Oxygen Glucose Deprivation Model
- 3D Cell Culture
- iPSC-derived Neurons
- Isolation and culture of neural stem/progenitor cells
- Animal Models
- Techinques
- Resource
- Equipment
-
Experiment Systems
- Order
- Careers
- Home
- Products
- Ionic Screening Panel
- Human CHRM3-FLAG Stable Cell Line-CHO
Human CHRM3-FLAG Stable Cell Line-CHO
The muscarinic M3 receptor is a 590-amino acid, 7-transmembrane protein. RT-PCR and radioligand binding assays detected M3 expression in the bladder, gastric and intestinal smooth muscle, brain (CNS) and the vestibular system. Muscarinic M3 receptors mediate contraction of airway and bladder smooth muscles. The receptors in the urothelium/suburothelium can also modulate the release of certain factors, which in turn may affect bladder function at the efferent or afferent axis. Blockade of M3 receptors can alleviate the symptoms of OAB. M3 receptors are also expressed myocardial tissues and are of potential roles in parasympathetic control of heart function under normal physiological conditions and in heart failure, myocardial ischemia and arrhythmias.
| Product Information | |
|---|---|
| Catalog #: | ACC-RG0318 |
| Gene Name | CHRM3 |
| Abbr | CHO-HuCHRM3-FLAG |
| Alias | CHRM3,HM3,EGBRS |
| Growth Properties | Adherent |
| Host Cell | CHO-K1 |
| Morphology | Epithelial-like |
| Shipping | Dry ice |
| Product Type | GPCR Expressing Cell |
| Species | Human |
| Product Format | frozen |
| searchKeyword | CHRM3,HM3,EGBRS |
Related Products
| Catalog | Product Name | Gene Name | Species | Morphology | Price |
|---|---|---|---|---|---|
| ACC-RG0014 | Human CHRM3 Stable Cell Line-U2OS | CHRM3 | Human | Epithelial | INQUIRY |
| ACC-RG0060 | Human CHRM3 Stable Cell Line-CHO | CHRM3 | Human | Epithelial-like | INQUIRY |
Inquiry