CRHR2 (Corticotropin Releasing Hormone Receptor 2) is a Protein Coding gene. Diseases associated with CRHR2 include Anxiety and Irritable Bowel Syndrome. Among its related pathways are Activation of cAMP-Dependent PKA and Peptide hormone metabolism. Gene Ontology (GO) annotations related to this gene include G protein-coupled receptor activity and hormone activity. An important paralog of this gene is CRHR1. The protein encoded by this gene belongs to the G-protein coupled receptor 2 family, and the subfamily of corticotropin releasing hormone receptor. This receptor shows high affinity for corticotropin releasing hormone (CRH), and also binds CRH-related peptides such as urocortin. CRH is synthesized in the hypothalamus, and plays an important role in coordinating the endocrine, autonomic, and behavioral responses to stress and immune challenge. Studies in mice suggest that this receptor maybe involved in mediating cardiovascular homeostasis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Product Information | |
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Catalog #: | ACC-RG1762 |
Gene Name | CRHR2 |
Abbr | CRHR2 |
Alias | CRHR2 |
Host Cell | CHO-K1/Gα15 |
Shipping | Dry ice |
Product Type | GPCR Expressing Cell |
Species | Human |
Product Format | Liquid nitrogen |
searchKeyword | CRHR2 |
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ACC-RG0029 | Human CRHR2-tGFP Stable Cell Line-CHO | CRHR2 | Human | Epithelial-like | INQUIRY |
ACC-RG0009 | Human CRHR2 Stable Cell Line-HEK293 | CRHR2 | Human | Epithelial | INQUIRY |
ACC-RG0236 | Human CRHR2-FLAG Stable Cell Line-HEK293T | CRHR2 | Human | Epithelial | INQUIRY |
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