CXCR3 is a 7-TM GPCR that is selective for the CXC chemokines IP10, I-TAC and MIG. Binding of IP10 and MIG to CXCR3 induces Ca2+ mobilization, chemotaxis and inflammatory responses of T lymphocytes, and also act as potent inhibitors of angiogenesis. CXCR3 is highly expressed in IL-2-activated T lymphocytes in vitro, and in T lymphocytes present in inflamed tissues in rheumatoid arthritis and multiple sclerosis. In vivo, neutralization of CXCR3 inhibits experimentally induced type I diabetes, peritonitis, and post-lung transplantation bronchiolitis obliterans syndrome.

Product Information
Catalog #:	ACC-RG1267
Gene Name	CXCR3
Abbr	CHO-HuCXCR3/Apoaequorin
Alias	CXCR3,GPR9,CD183,CKR L2,CMKAR3,IP10 R,MigR,CXC-R3,CXCR-3,GPR9,CD182,Mig-R,CKR-L2,IP10-R
Growth Properties	Adherent
Host Cell	CHO-K1
Morphology	Epithelial-like
Shipping	Dry ice
Product Type	GPCR Expressing Cell
Species	Human
Product Format	frozen
searchKeyword	CXCR3,GPR9,CD183,CKR L2,CMKAR3,IP10 R,MigR,CXC-R3,CXCR-3,GPR9,CD182,Mig-R,CKR-L2,IP10-R

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