This CXCR4 gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Product Information | |
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Catalog #: | ACC-RG1748 |
Gene Name | CXCR4 |
Abbr | CXCR4 |
Alias | CXCR4 |
Host Cell | CHO-K1/Gα15 |
Shipping | Dry ice |
Product Type | GPCR Expressing Cell |
Species | Human |
Product Format | Liquid nitrogen |
searchKeyword | CXCR4 |
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ACC-RG0222 | Human CXCR4-FLAG Stable Cell Line-HEK293T | CXCR4 | Human | Epithelial | INQUIRY |
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