Dopamine is a catecholamine neurotransmitter that functions in the CNS to control locomotor, cognitive, emotional and neurendocrine processes, and in the periphery to modulate cardiovascular, renal and gastrointestinal processes. The biological activities of dopamine are mediated by a family of five GPCRs. The D1 and D5 subtypes couple to Gs to increase intracellular cAMP, whereas the D2 , D3 and D4 subtypes couple to Gi to reduce cAMP. The D2 dopamine receptors have been of particular clinical interest due to their regulation of prolactin secretion and their affinity for antipsychotic drugs. The D2 receptor exists as two alternatively spliced isoforms differing in the insertion of a stretch of 29 amino acids in the third intracellular loop (D2S and D2L).

Product Information
Catalog #:	ACC-RG0652
Gene Name	DRD2
Abbr	CHO-HuDRD2/Galpha15
Alias	D2R,D2DR,DRD2
Growth Properties	Adherent
Host Cell	CHO
Morphology	Epithelial-like
Shipping	Dry ice
Product Type	GPCR Expressing Cell
Species	Human
Product Format	frozen
searchKeyword	D2R,D2DR,DRD2

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