The lipoxin A4 receptor ALX is also known as formyl peptide receptorlike 1 (FPRL1) or formyl peptide receptor 2 (FPR2). It shares 69% amino acid identity with FPR but displays low affinity for bacterial peptide N-formyl-methionylleucyl-phenylalanine (fMLF). ALX is highly expressed on neutrophils and monocytes and mediates cell chemotaxis. By interacting with a variety of exogenous and hostderived agonists, ALX may have important implications in the pathogenesis of human diseases such as HIV, Alzheimers disease (AD), amyloidosis and prion diseases.
Product Information | |
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Catalog #: | ACC-RG0279 |
Gene Name | FPR2 |
Abbr | HEK293T-HuFPR2-FLAG |
Alias | FPR2,FPRL1,ALXR,FMLP R II,FMLPX,FPR2A,FPRH2,HM63,LXA4R,RFP,FMLP-R-I,FPRH1,FPRL1 |
Growth Properties | Adherent |
Host Cell | HEK293T |
Morphology | Epithelial |
Shipping | Dry ice |
Product Type | GPCR Expressing Cell |
Species | Human |
Product Format | frozen |
searchKeyword | FPR2,FPRL1,ALXR,FMLP R II,FMLPX,FPR2A,FPRH2,HM63,LXA4R,RFP,FMLP-R-I,FPRH1,FPRL1 |
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