Galanin is a 29-30 amino acid peptide originally purified from intestine, but later found to be abundant in the CNS. It is widely distributed in tissues such as the brain, spinal cord and gut, and can regulate numerous processes including feeding, nociception, nerve regeneration, memory, neuroendocrine release, and gut secretion and contractility. Galanin elicits its physiological effects through the stimulation of at least three G protein-coupled receptors. GAL2 receptor couples predominantly to the activation of phospholipase C. It plays an important role in modulating neurite outgrowth and has been demonstrated to be the principal receptor subtype that mediates the protective effects of galanin in the hippocampus.
Product Information | |
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Catalog #: | ACC-RG1230 |
Gene Name | GALR2 |
Abbr | CHO-HuGALR2/Photina |
Alias | GALR2,GALNR2,GAL2-R,GALR-2,MGC125983,MGC125984 |
Growth Properties | Adherent |
Host Cell | CHO |
Morphology | Epithelial-like |
Shipping | Dry ice |
Product Type | GPCR Expressing Cell |
Species | Human |
Product Format | frozen |
searchKeyword | GALR2,GALNR2,GAL2-R,GALR-2,MGC125983,MGC125984 |
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