Proton-sensing receptor involved in pH homeostasis. May represents an osteoblastic pH sensor regulatingcell-mediated responses to acidosis in bone. Mediates its action by association with G proteins that stimulatesinositol phosphate (IP) production or Ca(2+) mobilization. The receptor is almost silent at pH 7.8 but fullyactivated at pH 6.8. Function also as a metastasis suppressor gene in prostate cancer (By similarity)
Product Information | |
---|---|
Catalog #: | ACC-RG1663 |
Gene Name | GPR68 |
Host Cell | CHO-K1/Gα15 |
Shipping | Dry Ice |
Product Type | GPCR Expressing Cell |
Species | Human |
Product Format | frozen |
searchKeyword | GPR68 |
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