The metabotropic glutamate receptors (mGluRs) have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group II and group III mGluRs are linked to the inhibition of the cyclic AMP cascade, but differ in agonist selectivity. Group III agonists include L-2-amino-4-phosphonobutyrate (L-AP4) and L-serine-O-phosphate. The human mGluR8 protein shares 67 to 70% sequence similarity with mGluR4 and mGluR7 and 99% amino acid identity with mouse mGluR8.
Product Information | |
---|---|
Catalog #: | ACC-RG0313 |
Gene Name | GRM8 |
Abbr | CHO-HuGRM8-FLAG |
Alias | GRM8,GLUR8,GPRC1H,mGlu8,MGLUR8,FLJ41058 |
Growth Properties | Adherent |
Host Cell | CHO-K1 |
Morphology | Epithelial-like |
Shipping | Dry ice |
Product Type | GPCR Expressing Cell |
Species | Human |
Product Format | frozen |
searchKeyword | GRM8,GLUR8,GPRC1H,mGlu8,MGLUR8,FLJ41058 |
Related Products
Catalog | Product Name | Gene Name | Species | Morphology | Price |
---|---|---|---|---|---|
ACC-RG0314 | Human GRM8-FLAG Stable Cell Line-HEK293T | GRM8 | Human | Epithelial | INQUIRY |
ACC-RG0312 | Human GRM8-FLAG Stable Cell Line-HEK293T Galphaqi5 | GRM8 | Human | Epithelial | INQUIRY |
Inquiry