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- Human HCAR2 Stable Cell Line-CHO-K1/Gα15
Human HCAR2 Stable Cell Line-CHO-K1/Gα15
Acts as a high affinity receptor for both nicotinic acid (also known as niacin) and(D)-beta-hydroxybutyrate and mediates increased adiponectin secretion and decreased lipolysis throughG(i)-protein-mediated inhibition of adenylyl cyclase. This pharmacological effect requires nicotinic acid dosesthat are much higher than those provided by a normal diet. Mediates nicotinic acid-induced apoptosis in matureneutrophils. Receptor activation by nicotinic acid results in reduced cAMP levels which may affect activity ofcAMP-dependent protein kinase A and phosphorylation of target proteins, leading to neutrophil apoptosis.
| Product Information | |
|---|---|
| Catalog #: | ACC-RG1680 |
| Gene Name | HCAR2 |
| Host Cell | CHO-K1/Gα15 |
| Shipping | Dry Ice |
| Product Type | GPCR Expressing Cell |
| Species | Human |
| Product Format | frozen |
| searchKeyword | HCAR2 |
Related Products
| Catalog | Product Name | Gene Name | Species | Morphology | Price |
|---|---|---|---|---|---|
| ACC-RG1315 | Human HCAR2/Apoaequorin Stable Cell Line-CHO | HCAR2 | Human | Epithelial-like | INQUIRY |
| ACC-RG0337 | Human HCAR2-FLAG Stable Cell Line-CHO | HCAR2 | Human | Epithelial-like | INQUIRY |
| ACC-RG1193 | Human HCAR2 Validated Stable Cell Line-CHO | HCAR2 | Human | Epithelial-like | INQUIRY |
Our products are only for research use. Not intended for any clinical or diagnostic use.
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