- Home
-
Screening
- Ionic Screening Service
-
Ionic Screening Panel
- Ligand Gated Ion Channels
- Glycine Receptors
- 5-HT Receptors3
- Nicotinic Acetylcholine Receptors
- Ionotropic Glutamate-gated Receptors
- GABAa Receptors
- Cystic Fibrosis Transmembrane Conductance Regulators (CFTR)
- ATP gated P2X Channels
- Voltage-Gated Ion Channels
- Calcium Channels
- Chloride Channels
- Potassium Channels
- Sodium Channels
- ASICs
- TRP Channels
- Other Ion Channels
- Stable Cell Lines
- Cardiology
- Neurology
- Ophthalmology
-
Platform
-
Experiment Systems
- Xenopus Oocyte Screening Model
- Acute Isolated Cardiomyocytes
- Acute Dissociated Neurons
- Primary Cultured Neurons
- Cultured Neuronal Cell Lines
- iPSC-derived Cardiomyocytes/Neurons
- Acute/Cultured Organotypic Brain Slices
- Oxygen Glucose Deprivation Model
- 3D Cell Culture
- iPSC-derived Neurons
- Isolation and culture of neural stem/progenitor cells
- Animal Models
- Techinques
- Resource
- Equipment
-
Experiment Systems
- Order
- Careers
Human HCAR2 Stable Cell Line-CHO-K1/Gα15
Acts as a high affinity receptor for both nicotinic acid (also known as niacin) and(D)-beta-hydroxybutyrate and mediates increased adiponectin secretion and decreased lipolysis throughG(i)-protein-mediated inhibition of adenylyl cyclase. This pharmacological effect requires nicotinic acid dosesthat are much higher than those provided by a normal diet. Mediates nicotinic acid-induced apoptosis in matureneutrophils. Receptor activation by nicotinic acid results in reduced cAMP levels which may affect activity ofcAMP-dependent protein kinase A and phosphorylation of target proteins, leading to neutrophil apoptosis.
| Product Information | |
|---|---|
| Catalog #: | ACC-RG1680 |
| Gene Name: | HCAR2 |
| Host Cell | CHO-K1/Gα15 |
| Product Format | frozen |
| Product Type | GPCR Expressing Cell |
| searchKeyword | HCAR2 |
| Shipping | Dry Ice |
| Species | Human |
Related Products
| Catalog | Product Name | Gene Name | Species | Morphology | Price |
|---|---|---|---|---|---|
| ACC-RG1193 | Human HCAR2 Validated Stable Cell Line-CHO | HCAR2 | Human | Epithelial-like | INQUIRY |
Our products are only for research use. Not intended for any clinical or diagnostic use.
Inquiry