5-Hydroxytryptamine (5-HT, also commonly known as serotonin) is synthesized in enterochromaffin cells in the intestine and in serotonergic nerve terminals. In the periphery, 5-HT mediates gastrointestinal motility, platelet aggregation, and contraction of blood vessels. Many functions of the central nervous system are influenced by 5-HT, including sleep, motor activity, sensory perception, arousal and appetite. A family of 12 GPCRs and one ion channel mediate the biological effects of 5-HT. The 5-HT2B receptor, which couples to Gq/11 to increase intracellular calcium, is expressed in embryonic and adult cardiovascular tissues, gut and brain from the rat, mouse, and human species. A role for 5-HT2B receptors was suggested in the cardiopathy associated with fenfluramine.

Product Information
Catalog #:	ACC-RG0752
Gene Name	HTR2B
Abbr	CHO -HuHTR2B/Galpha15
Alias	HTR2B,5 HT(2B),5 HT2B,5-HT-2B,5-HT2B,5-HT(2B)
Growth Properties	Adherent
Host Cell	CHO
Morphology	Epithelial-like
Shipping	Dry ice
Product Type	GPCR Expressing Cell
Species	Human
Product Format	frozen
searchKeyword	HTR2B,5 HT(2B),5 HT2B,5-HT-2B,5-HT2B,5-HT(2B)

Related Products

Catalog	Product Name	Gene Name	Species	Morphology	Price
ACC-RG0387	Human HTR2B-FLAG Stable Cell Line-HEK293T	HTR2B	Human	Epithelial	INQUIRY
ACC-RG0388	Human HTR2B-FLAG Stable Cell Line-CHO	HTR2B	Human	Epithelial-like	INQUIRY
ACC-RG0779	Human HTR2B Stable Cell Line-CHO	HTR2B	Human	Epithelial-like	INQUIRY