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- Human PTGER1-FLAG Stable Cell Line-HEK293T
Human PTGER1-FLAG Stable Cell Line-HEK293T
EP1 receptor (or PTGER1) is a receptor or prostaglandin E2 (PGE2). The receptor may play a role in the smooth muscle contractile response to PGE2 in various tissues. EP1 receptor transactivates EGFR thus activating Akt, while activation of EGFR by its cognate ligand EGF increased COX-2 expression and PGE2 production. This crosstalk between EP1 and EGFR signaling synergistically promotes cancer cell growth and invasion. Some EP1-specific antagonists inhibit osteoclast formation induced by RANKL from the early stage of osteoclastogenesis. This cell line expresses EP1 cDNA that is identical to GenBank NM_000955.2 except for 1 sense mutation, Thr→Ala at position 70. It has been reported as a natural variant.
| Product Information | |
|---|---|
| Catalog #: | ACC-RG0359 |
| Gene Name | PTGER1 |
| Abbr | HEK293T-HuPTGER1-FLAG |
| Alias | PTGER1 |
| Growth Properties | Adherent |
| Host Cell | HEK293T |
| Morphology | Epithelial |
| Shipping | Dry ice |
| Product Type | GPCR Expressing Cell |
| Species | Human |
| Product Format | frozen |
| searchKeyword | PTGER1 |
Related Products
| Catalog | Product Name | Gene Name | Species | Morphology | Price |
|---|---|---|---|---|---|
| ACC-RG1641 | Human PTGER1 Stable Cell Line-HEK293 | PTGER1 | Human | INQUIRY |
Our products are only for research use. Not intended for any clinical or diagnostic use.
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