The protein encoded by this gene is a member of the G-protein coupled receptor family 2. This protein is a receptor for parathyroid hormone (PTH) and for parathyroid hormone-like hormone (PTHLH). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in this receptor are known to be the cause of Jansen's metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), as well as enchodromatosis. Two transcript variants encoding the same protein have been found for this gene.
|Product Type||GPCR Expressing Cell|
|Catalog||Product Name||Gene Name||Species||Morphology||Price|
|ACC-RG0541||Human PTH1R/Gs Stable Cell Line-CHO||PTH1R||Human||Epithelial-like||INQUIRY|
|ACC-RG0748||Human PTH1R/Galpha15 Stable Cell Line-Chem-1||PTH1R||Human||INQUIRY|
|ACC-RG1591||Human PTH1R/beta-Arrestin Stable Cell Line-CHO||PTH1R||Human||Epithelial-like||INQUIRY|
|ACC-RG1744||Human PTH1R Stable Cell Line-HEK293T||PTH1R||Human||INQUIRY|