RAMP1 (Receptor Activity Modifying Protein 1) is a Protein Coding gene. Diseases associated with RAMP1 include Migraine With Or Without Aura 1. Among its related pathways are Presynaptic function of Kainate receptors and Oxytocin signaling pathway. Gene Ontology (GO) annotations related to this gene include coreceptor activity. An important paralog of this gene is RAMP2. The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP1) protein, CRLR functions as a CGRP receptor. The RAMP1 protein is involved in the terminal glycosylation, maturation, and presentation of the CGRP receptor to the cell surface. Alternative splicing results in multiple transcript variants encoding different isoforms. CALCR (Calcitonin Receptor) is a Protein Coding gene. Diseases associated with CALCR include Osteoporosis and Bone Mineral Density Quantitative Trait Locus 15. Among its related pathways are Presynaptic function of Kainate receptors and RANK Signaling in Osteoclasts. Gene Ontology (GO) annotations related to this gene include G protein-coupled receptor activity and transmembrane signaling receptor activity.

Product Information
Catalog #:	ACC-RG1758
Gene Name	RAMP1+CALCR
Abbr	RAMP1+CALCR
Alias	RAMP1+CALCR
Host Cell	CHO-K1/Gα15
Shipping	Dry ice
Product Type	GPCR Expressing Cell
Species	Human
Product Format	Liquid nitrogen
searchKeyword	RAMP1+CALCR