Somatostatin receptors are activated by somatostatin secreted from nerve and endocrine cells. The Somatostatin Receptors (SSTRs) are expressed in a tissue-specific manner and involved in the regulation of secretion of insulin, glucagon and growth hormone as well as cell growth induced by neuronal excitation in both the central and peripheral nervous systems. Aberrent expression of somatostatin receptors is known in a large number of human tumours. SSTR2 is expressed in highest levels in the stomach, jejunum, cerebrum, thyroid and kidney. Its gene expression is lost in 90% of human pancreatic adenocarcinomas while SSTR2 expression in neuroblastoma correlates positively to overall and event-free survival. Expression of SSTR-2 and SSTR-5 may be important in the growth inhibitory effect of somatostatin in human pancreatic cancer.

Product Information
Catalog #:	ACC-RG0398
Gene Name	SSTR2
Abbr	CHO-K1 Galpha16-HuSSTR2-FLAG
Alias	SSTR2,SRIF-1,SS2R
Growth Properties	Adherent
Host Cell	CHO-K1 Galpha16
Morphology	Epithelial-like
Shipping	Dry ice
Product Type	GPCR Expressing Cell
Species	Human
Product Format	frozen
searchKeyword	SSTR2,SRIF-1,SS2R

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