L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. The metabotropic glutamate receptors, which are G protein-coupled receptors, have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms and pharmacologic properties. Group II and group III receptors are linked to the inhibition of the cyclic AMP cascade, but differ in their agonist selectivity. Group III agonists include L-2-amino-4-phosphonobutyrate (LAP4) and L-serine-O-phosphate.

Product Information
Catalog #:	ACC-RG0305
Gene Name	Grm4
Abbr	HEK293T-RatGrm4-FLAG
Alias	GRM4,mGluR4
Growth Properties	Adherent
Host Cell	HEK293T
Morphology	Epithelial
Shipping	Dry ice
Product Type	GPCR Expressing Cell
Species	Rat
Product Format	frozen
searchKeyword	GRM4,mGluR4

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