This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. The adrenergic receptors are a class of G protein-coupled receptors that are targets of the catecholamines, especially noradrenaline (norepinephrine) andadrenaline (epinephrine). Although dopamine is a catecholamine, its receptors are in a different category. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. Many cells possess these receptors, and the binding of an agonist will generally cause a sympathetic response (i.e. the fight-or-flight response). Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes.
Product Information | |
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Catalog #: | ACC-RG0025 |
Gene Name | ADRB2 |
Abbr | CHO-HuADRB2-tGFP |
Alias | ADRB2,ADRB2R,ADRBR,B2AR,BAR,BETA2AR |
Growth Properties | Adherent |
Host Cell | CHO-K1 |
Morphology | Epithelial-like |
Shipping | Dry ice |
Product Type | GPCR Expressing Cell |
Species | Human |
Product Format | frozen |
searchKeyword | ADRB2,ADRB2R,ADRBR,B2AR,BAR,BETA2AR |
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ACC-RG0175 | Human ADRB2-FLAG Stable Cell Line-CHO | ADRB2 | Human | Epithelial-like | INQUIRY |
ACC-RG0058 | Human ADRB2 Stable Cell Line-CHO | ADRB2 | Human | Epithelial-like | INQUIRY |
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