The activity of Arginine Vasopressin receptor 1A (AVPR1A) is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. Arginine Vasopressin 1A receptor belongs to the same subfamily of G-protein coupled receptors of AVPR1B, V2R and Oxytocin receptors. The receptor mediates cell contraction and proliferation, platelet aggregation, release of coagulation factor and glycogenolysis. V1A is coupled to Gq/11 proteins and is found at high density on smooth muscle cells. It is involved in regulation of blood pressure through arterial vasoconstriction and has been found to stimulate VEGF secretion. AVPR1A is widely expressed in the brain and it has been implicated in social behaviours, including affiliation and attachment and related to diseases as autism.

Product Information
Catalog #:	ACC-RG0018
Gene Name	AVPR1A
Abbr	HEK293-HuAVPR1A
Alias	AVPR1A,AVPR V1a,AVPR1,V1aR
Growth Properties	Adherent
Host Cell	HEK293
Morphology	Epithelial
Shipping	Dry ice
Product Type	GPCR Expressing Cell
Species	Human
Product Format	frozen
searchKeyword	AVPR1A,AVPR V1a,AVPR1,V1aR

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