Arginine vasopressin (AVP) is a 9 amino acid peptide that functions as an antidiuretic, vasoconstrictor and neurotransmitter. The three vasopressin receptors, V1A, V1B and V2, are GPCRs; V1A and V1B couple to Gq and calcium release, whereas V2 couples to Gs. The V1B receptor is expressed prominently in the anterior pituitary, where it mediates vasopressin-induced release of ACTH. A selective antagonist of V1B has recently been developed and shown to reduce depression, anxiety, and aggression in rodents.
Product Information | |
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Catalog #: | ACC-RG1226 |
Gene Name | AVPR1B |
Abbr | 1321N1-HuAVPR1B Validated |
Alias | AVPR1B,AVPR3,V1bR |
Growth Properties | Adherent |
Host Cell | 1321N1 |
Morphology | Glial |
Shipping | Dry ice |
Product Type | GPCR Expressing Cell |
Species | Human |
Product Format | frozen |
searchKeyword | AVPR1B,AVPR3,V1bR |
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