Bradykinin, a 9 aa peptide, is generated in pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy. Two types of G-protein coupled receptors have been found which bind bradykinin and mediate responses to these pathophysiologic conditions. The protein encoded by this gene is one of these receptors and is synthesized de novo following tissue injury. Receptor binding leads to an increase in the cytosolic calcium ion concentration, ultimately resulting in chronic and acute inflammatory responses. Several transcript variants encoding different isoforms have been found for this gene.

Product Information
Catalog #:	ACC-RG1132
Gene Name	BDKRB1
Abbr	CHO-HuBDKRB1 Validated
Alias	BDKRB1,B1BKR,B1R,BKB1R,BKR1,BRADYB1
Growth Properties	Adherent
Host Cell	CHO-K1
Morphology	Epithelial-like
Shipping	Dry ice
Product Type	GPCR Expressing Cell
Species	Human
Product Format	frozen
searchKeyword	BDKRB1,B1BKR,B1R,BKB1R,BKR1,BRADYB1

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