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- Human C3AR1 Validated Stable Cell Line-CHO
Human C3AR1 Validated Stable Cell Line-CHO
C3a, along with C4a and C5a, is a 77 amino acid anaphylotoxin generated by proteolytic cleavage during activation of the complement pathway. The anaphylotoxins strongly promote inflammation by recruiting leukocytes, particularly basophils, eosinophils, neutrophils and monocyte. The proinflammatory properties of C3a are mediated by interaction between the peptide and a 7-TM G-protein coupled receptor, C3aR. Genetic and pharmacological inhibition of C3a/C3aR interaction indicates an important role for C3aR in allergic asthma. C3a/C3aR also enhances the effect of SDF-1 in promoting retention of haematopoietic stem/progenitor cells within the bone marrow.
| Product Information | |
|---|---|
| Catalog #: | ACC-RG1125 |
| Gene Name | C3AR1 |
| Abbr | CHO-HuC3AR1 Validated |
| Alias | C3AR1,AZ3B,C3AR,C3a-R,HNFAG09 |
| Growth Properties | Adherent |
| Host Cell | CHO-K1 |
| Morphology | Epithelial-like |
| Shipping | Dry ice |
| Product Type | GPCR Expressing Cell |
| Species | Human |
| Product Format | frozen |
| searchKeyword | C3AR1,AZ3B,C3AR,C3a-R,HNFAG09 |
Related Products
| Catalog | Product Name | Gene Name | Species | Morphology | Price |
|---|---|---|---|---|---|
| ACC-RG1245 | Human C3AR1/Apoaequorin Stable Cell Line-CHO | C3AR1 | Human | Epithelial-like | INQUIRY |
| ACC-RG0177 | Human C3AR1-FLAG Stable Cell Line-HEK293T | C3AR1 | Human | Epithelial | INQUIRY |
Our products are only for research use. Not intended for any clinical or diagnostic use.
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