This CACNA2D4 gene encodes a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.
| Product Information | |
|---|---|
| Catalog #: | ACC-RI0069 |
| Gene Name: | CACNA2D4 |
| Abbr | CHO-HuCACNA1A/CACNB3/CACNA2D2 |
| Alias | Cav2.1/β3/α2δ2,CACNA1A/CACNB3/CACNA2D2,CACNA2D4 |
| Channel Subgroup | P/Q-type channels |
| Channel Type | Calcium channel |
| Growth Properties | Adherent |
| Host Cell | CHO |
| Morphology | Epithelial-like |
| Product Format | frozen |
| Product Type | Ion Channel Expressing Cell |
| searchKeyword | Cav2.1/β3/α2δ2,CACNA1A/CACNB3/CACNA2D2,CACNA2D4 |
| Shipping | Dry ice |
| Species | Human |
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