This CACNA2D4 gene encodes a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.

Product Information
Catalog #:	ACC-RI0069
Gene Name	CACNA2D4
Abbr	CHO-HuCACNA1A/CACNB3/CACNA2D2
Alias	Cav2.1/β3/α2δ2,CACNA1A/CACNB3/CACNA2D2,CACNA2D4
Growth Properties	Adherent
Host Cell	CHO
Morphology	Epithelial-like
Shipping	Dry ice
Product Type	Ion Channel Expressing Cell
Channel Type	Calcium channel
Channel Subgroup	P/Q-type channels
Species	Human
Product Format	frozen
searchKeyword	Cav2.1/β3/α2δ2,CACNA1A/CACNB3/CACNA2D2,CACNA2D4