The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP1) protein, CRLR functions as a CGRP receptor. The RAMP1 protein is involved in the terminal glycosylation, maturation, and presentation of the CGRP receptor to the cell surface.
Product Information | |
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Catalog #: | ACC-RG1135 |
Gene Name | RAMP1 |
Abbr | CHO-HuCALCRL+RAMP1 Validated |
Alias | RAMP1 |
Growth Properties | Adherent |
Host Cell | CHO-K1 |
Morphology | Epithelial-like |
Shipping | Dry ice |
Product Type | GPCR Expressing Cell |
Species | Human |
Product Format | frozen |
searchKeyword | RAMP1 |
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Catalog | Product Name | Gene Name | Species | Morphology | Price |
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ACC-RG1256 | Human CALCRL+RAMP1/Apoaequorin Stable Cell Line-CHO | RAMP1 | Human | Epithelial-like | INQUIRY |
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