The protein encoded by this gene is a G protein-coupled receptor that is expressed in the parathyroid hormone (PTH)-producing chief cells of the parathyroid gland, and the cells lining the kidney tubule. It senses small changes in circulating calcium concentration and couples this information to intracellular signaling pathways that modify PTH secretion or renal cation handling, thus this protein plays an essential role in maintaining mineral ion homeostasis. Mutations in this gene cause familial hypocalciuric hypercalcemia, familial, isolated hypoparathyroidism, and neonatal severe primary hyperparathyroidism.

Product Information
Catalog #:	ACC-RG1655
Gene Name	CASR
Host Cell	CHO-K1
Shipping	Dry Ice
Product Type	GPCR Expressing Cell
Species	Human
Product Format	frozen
searchKeyword	CASR

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