Cholecystokinin (CCK) is a neuropeptide which is widely distributed in the mammalian central nervous system. Two CCK receptors have been identified to mediate the effects of CCK/gastrin family: CCKA (or CCK-1) receptor and CCKB (or CCK-2 or gastrin receptor). The CCKB receptor is the predominant subtype in the CNS where it is widely distributed, however, it also occurs in abundance in the gastro-intestinal tract. CCKB receptors have been found to be most abundant in the cerebral cortex, cerebellum, basal ganglia, and amygdale. Animal and human studies using CCKB receptor antagonists have suggested that anxiety, panic attacks, analgesia, and satiety may be modulated through the CCKB receptor.

Product Information
Catalog #:	ACC-RG1150
Gene Name	CCKBR
Abbr	1321N1-HuCCKBR Validated
Alias	CCKBR,CCK-BR,CCK2-R,GASR,CCK-B,CCK2R
Growth Properties	Adherent
Host Cell	1321N1
Morphology	Glial
Shipping	Dry ice
Product Type	GPCR Expressing Cell
Species	Human
Product Format	frozen
searchKeyword	CCKBR,CCK-BR,CCK2-R,GASR,CCK-B,CCK2R

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