This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The ligands of this receptor include macrophage inflammatory protein 1 alpha (MIP-1 alpha), regulated on activation normal T expressed and secreted protein (RANTES), monocyte chemoattractant protein 3 (MCP-3), and myeloid progenitor inhibitory factor-1 (MPIF-1). Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. Knockout studies of the mouse homolog suggested the roles of this gene in host protection from inflammatory response, and susceptibility to virus and parasite. This gene and other chemokine receptor genes, including CCR2, CCRL2, CCR3, CCR5 and CCXCR1, are found to form a gene cluster on chromosome 3p.

Product Information
Catalog #:	ACC-RG1718
Gene Name	CCR1
Host Cell	HEK293T Gαqi5
Shipping	Dry ice
Product Type	GPCR Expressing Cell
Species	Human
Product Format	frozen
searchKeyword	CCR1

Related Products

Catalog	Product Name	Gene Name	Species	Morphology	Price
ACC-RG0041	Human CCR1-SNAP Stable Cell Line-HEK293	CCR1	Human	Epithelial	INQUIRY
ACC-RG1658	Human CCR1 Stable Cell Line-CHO-K1/Gα15	CCR1	Human		INQUIRY
ACC-RG1138	Human CCR1 Validated Stable Cell Line-CHO	CCR1	Human	Epithelial-like	INQUIRY
ACC-RG0197	Human CCR1-FLAG Stable Cell Line-HEK293T	CCR1	Human	Epithelial	INQUIRY