CCR1 is a GPCR that binds to a variety of CC ligands, including MIP-1, RANTES, MCP-3, HCC-1, HCC-2, HCC-4, and MPIF-1. Lymphocytes, macrophages, dendritic cells, and GM-CSF-activated neutrophils express CCR1. Two selective, non-peptide small molecule antagonists of CCR1, BX-471 and CP-481,715, have been synthesized. Pharmacological and genetic targeting of CCR1, either alone or in combination with cyclosporin A, reduces cardiac and renal allograft rejection, allergic encephalomyelitis, and renal fibrosis in experimental models.

Product Information
Catalog #:	ACC-RG1138
Gene Name	CCR1
Abbr	CHO-HuCCR1 Validated
Alias	CCR1,CMKBR1,SCYAR1,CKR 1,MIP1aR,CCR-1,CKR1,CKR-1,HM145,CMKBR1,SCYAR1,
Growth Properties	Adherent
Host Cell	CHO-K1
Morphology	Epithelial-like
Shipping	Dry ice
Product Type	GPCR Expressing Cell
Species	Human
Product Format	frozen
searchKeyword	CCR1,CMKBR1,SCYAR1,CKR 1,MIP1aR,CCR-1,CKR1,CKR-1,HM145,CMKBR1,SCYAR1,

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