Human CCR2 Stable Cell Line-CHO

Chemokines are a family of low molecular weight secreted proteins that act as leukocyte specifie chemoattractants. There are over 40 known chemokines which can be divided into four families: CXC, CC, C and CX3C. The CC-chemokines MCP-1,2,3,4 bind and activate CCR2 receptors. CCR2 receptors belong to the GPCR family and couple to the Gi signal pathway. CCR2 receptors are expressed on monocytes, macrophages, basophils, mast cells, T lymphocytes, NK cells and dendritic cells. There are two alternatively spliced forms of CCR2 receptors CCR2A and CCR2B, which differ only in their carboxyl-terminal tails. CCR2 receptors plays important roles in the recruitment of monocytes/macrophages, T cells and relates to many diseases such as inflammation, HIV, and pulmonary fibrosis.

Product Information
Catalog #:	ACC-RG0823
Gene Name	CCR2
Abbr	CHO-HuCCR2
Alias	CCR2,CMKBR2,CC CKR 2,CD192,CKR2,FLJ78302,MCP 1 R,CCR2A,CCR2B,CKR2A,CKR2B,MCP-1-R,CC-CKR-2
Growth Properties	Adherent
Host Cell	CHO-K1
Morphology	Epithelial-like
Shipping	Dry ice
Product Type	GPCR Expressing Cell
Species	Human
Stability	12 passages of continuous culture (6 weeks) at 2 passages/week
Product Format	frozen
searchKeyword	CCR2,CMKBR2,CC CKR 2,CD192,CKR2,FLJ78302,MCP 1 R,CCR2A,CCR2B,CKR2A,CKR2B,MCP-1-R,CC-CKR-2