Human CCR5-SNAP Stable Cell Line-HEK293

This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemokine receptor gene cluster region. Two transcript variants encoding the same protein have been found for this gene

Product Information
Catalog #:	ACC-RG0042
Gene Name	CCR5
Abbr	HEK293-HuCCR5-SNAP
Alias	CCR5,CMKBR5,CD195,CKR 5,CKR5,CCR-5,CKR-5,CCCKR5,CMKBR5,CC-CKR-5
Growth Properties	Adherent
Host Cell	HEK293
Morphology	Epithelial
Shipping	Dry ice
Product Type	GPCR Expressing Cell
Species	Human
Product Format	frozen
searchKeyword	CCR5,CMKBR5,CD195,CKR 5,CKR5,CCR-5,CKR-5,CCCKR5,CMKBR5,CC-CKR-5