This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. This gene is located at the chemokine receptor gene cluster region.

Product Information
Catalog #:	ACC-RG1143
Gene Name	CCR8
Abbr	CHO-HuCCR8 Validated
Alias	CCR8,CMKBR8,CMKBRL2,CDw198,CKR L1,CY6,GPR CY6,TER1,CCR-8,CKRL1,CMKBR8,GPRCY6,CMKBRL2,CC-CKR-8,MGC129966,MGC129973
Growth Properties	Adherent
Host Cell	CHO-K1
Morphology	Epithelial-like
Shipping	Dry ice
Product Type	GPCR Expressing Cell
Species	Human
Product Format	frozen
searchKeyword	CCR8,CMKBR8,CMKBRL2,CDw198,CKR L1,CY6,GPR CY6,TER1,CCR-8,CKRL1,CMKBR8,GPRCY6,CMKBRL2,CC-CKR-8,MGC129966,MGC129973

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