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- Human CHRM4/Rat Kcnj3/Mouse Kcnj6 Stable Cell Line-HEK293
Human CHRM4/Rat Kcnj3/Mouse Kcnj6 Stable Cell Line-HEK293
Stimulation of Gi-coupled receptors in heart and brain activates G-protein-gated inward rectifier K+ channels (GIRK) via Gbetagamma (Dascal, N. 2001). This activity can be detected using a GIRK-mediated thallium flux assay described by Niswender et al., 2008. This assay is compatible with HTS and represents a novel and a sensitive assay for detecting Gi/o -coupled GPCRs.
| Product Information | |
|---|---|
| Catalog #: | ACC-RG0879 |
| Gene Name | Kcnj6 |
| Abbr | HEK293-HuCHRM4/rKcnj3/mKcnj6 |
| Alias | KCNJ6,GIRK-2,wv,BIR1,GIRK2,KATP2,KCNJ7,Kir3.2,weaver |
| Growth Properties | Adherent |
| Host Cell | HEK293 |
| Morphology | Epithelial |
| Shipping | Dry ice |
| Product Type | GPCR Expressing Cell |
| Species | Mouse |
| Product Format | frozen |
| searchKeyword | KCNJ6,GIRK-2,wv,BIR1,GIRK2,KATP2,KCNJ7,Kir3.2,weaver |
Our products are only for research use. Not intended for any clinical or diagnostic use.
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