CHRNA2 (Cholinergic Receptor Nicotinic Alpha 2 Subunit) is a Protein Coding gene. Diseases associated with CHRNA2 include Epilepsy, Nocturnal Frontal Lobe, 4 and Autosomal Dominant Nocturnal Frontal Lobe Epilepsy. Among its related pathways are Transmission across Chemical Synapses and Postsynaptic nicotinic acetylcholine receptors. Gene Ontology (GO) annotations related to this gene include drug binding. An important paralog of this gene is CHRNA4. This CHRNA2 gene encodes an alpha subunit that is widely expressed in the brain. The proposed structure for nAChR subunits is a conserved N-terminal extracellular domain followed by three conserved transmembrane domains, a variable cytoplasmic loop, a fourth conserved transmembrane domain, and a short C-terminal extracellular region. Mutations in this gene cause autosomal dominant nocturnal frontal lobe epilepsy type 4. Single nucleotide polymorphisms (SNPs) in this gene have been associated with nicotine dependence.

Product Information
Catalog #:	ACC-RI0019
Gene Name	CHRNA2
Abbr	HEK293-HuCHRNA2
Alias	CHRNA2
Growth Properties	Adherent
Host Cell	HEK293
Morphology	Epithelial
Shipping	Dry ice
Product Type	Ion Channel Expressing Cell
Channel Type	Ligand-gated Ion Channel
Channel Subgroup	Acetylcholine Receptor
Species	Human
Product Format	frozen
searchKeyword	CHRNA2