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Human CHRNA3/CHRNB4 Stable Cell Line-CHO

Nicotinic receptors (nAChR) are acetylcholine-activated non-selective cation channels that mediate excitatory neurotransmission. The receptor-channels are configured as hetero- or homopentamers. The human CHRNA3 and CHRNB4 genes encode a cationic-selective, ionotropic alpha3/beta 4 nicotinic acetylcholine receptor (nAChR). Channels that contain a3 subunits typically have lower Ca2+ permeability compared to those containing a7 subunits. Therefore, alpha7 nAChRs are particularly important in regulation of Ca2+-dependent signalling pathways. Tissue distribution also differs with alpha3/beta 4 receptors prominent in autonomic ganglia and alpha7 receptors widely distributed in the CNS.

Product Information
Catalog #:  ACC-RI0061
Gene Name CHRNB4
Abbr CHO-HuCHRNA3/CHRNB4
Alias CHRNB4
Growth Properties Adherent
Host Cell CHO-K1
Morphology Epithelial-like
Shipping Dry ice
Product Type Ion Channel Expressing Cell
Channel Type Nicotinic Acetylcholine Receptor
Species Human
Product Format frozen
searchKeyword CHRNB4
Our products are only for research use. Not intended for any clinical or diagnostic use.

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